Golden Thinker ® – Encyclopedia of Substances – DMAE

Also known as 2-Dimethyl Aminoethanol, , Acéglumate de Déanol2-Dimethylaminoethanol, Acétamido-benzoate de Déanol, , Bisorcate de Déanol, Benzilate de Déanol Cyclohexylpropionate de Déanol, Deanol Aceglumate Déanol,, Deanol Acetamidobenzoate and Deanol Benzilate it is one of the many neurotransmitters used by the body to convey the nerve messages from one nerve to the next where they do not have a physical contact. The chemical hence helps the body transmit the nerve messages. It is naturally found in abundance in all fish and especially in Salmon.

Historical Context DMAE has long been used as a supplement to enhance the brain function and protect the nervous system from a number of natural and pathogenic degradation processes. The chemical was not known as such until 1990’s and it was used in only the unsaturated forms as it occurs in nature. The most common source of this chemical is the Salmon fish. People used it due to its effects on the CNS and male reproductive systems. In the 1990’s the actual active agent DMAE was identified and isolated and since then it is being used as a supplement chiefly to enhance the brain power and also to increase male sexual powers.

Mode of Action

DMAE is a precursor to the chemical known as Choline. Choline, in turn, makes the chemical known as acetylcholine which an important functional component of the nerve impulse transmission system in the body. Having higher levels of DMAE means that the nerve impulse delivery will be smoother and hence the nervous system will perform better both in the cognitive and the motor domains. Talking about the effects on the sexual system, the chemical acetylcholine stimulates the adrenal glands located on the top of the kidneys to secrete more adrenaline which in turn increases the testosterone secretion by the testicles. This is the chemical playing the major role in


The effects of the supplement on the body are phenomenal but short lived. The effects on the body are

  • Better cognitive function as long as the active agent of the supplement is in the blood
  • Better motor functions meaning that the body is more responsive to the responses being well-timed and perfectly coordinated.
  • Increased libido
  • Increased overall activity of the body due to adrenaline Apart from all these, the prolonged use of the supplement has also shown a permanent improvement in the brain and central nervous system of the users.

This may possibly be due to the nerve supporting abilities of the active agent which helps protect the nerves by enhancing the protective coating around them.

Side Notes

In the lab study of the supplement, none of the active agents or its derivatives has shown the evidence of adverse side effects on the lab animals or the human volunteers. The active agent has a half-life of about 3 hours in the bloodstream and is secreted mainly through the urinary system. To have the fullest benefits, two to three doses are recommended in 24 hours.

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